2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-121618R
    α-Thujone (Standard)
    		Inhibitor
    α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.
    α-Thujone (Standard)
  • HY-17581R
    Buparvaquone (Standard)
    		Inhibitor
    Buparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
    Buparvaquone (Standard)
  • HY-B1400R
    Diiodohydroxyquinoline (Standard)
    		Inhibitor
    Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas.
    Diiodohydroxyquinoline (Standard)
  • HY-173027
    SPB07935
    		Inhibitor
    SPB07935 inhibits the plasmepsin II in Plasmodium falciparum and can be used as an antimalarial agent. SPB07935 regulates the life cycle of P. falciparum, inhibits the growth of Plasmodium strains FcB1 and 3D7 with IC50 of 8 μM and 4.7 μM.
    SPB07935
  • HY-12082
    GSK369796
    		Inhibitor
    GSK369796 is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.
    GSK369796
  • HY-P1638
    Isariin A
    		Inhibitor
    Isariin A is a cyclodepsipeptide isolated from the fungus Isaria cretacea, which exhibits antimalarial activity.
    Isariin A
  • HY-129130
    Canthin-6-one N-oxide
    		Inhibitor
    Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active antiparasitic agent with limited activity.
    Canthin-6-one N-oxide
  • HY-133709
    β-Aflatrem
    		Inhibitor
    β-Aflatrem is an insecticide metabolite from the sclerotium of Aspergillus flavus that exhibits significant activity against the corn borer H. zea.
    β-Aflatrem
  • HY-173213
    Antileishmanial agent-33
    		Inhibitor
    Antileishmanial agent-33 (4e), a hybrid compound of grandisin and machilin G, shows moderate activity on promastigotes (IC50 of 38.1 μM). Antileishmanial agent-33 (4e) shows potential as an antileishmanial agent for the research of cutaneous leishmaniasis (CL).
    Antileishmanial agent-33
  • HY-B1881R
    Pirimiphos-methyl (Standard)
    		Inhibitor
    Pirimiphos-methyl (Standard) is the analytical standard of Pirimiphos-methyl (HY-B1881). This product is intended for research and analytical applications. Pirimiphos-methyl is an organophosphorus insecticide and acaricide that can inhibit AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, snout beetles, moths and Ephestia cautella during storage of agricultural grains.
    Pirimiphos-methyl (Standard)
  • HY-107566A
    Conessine dihydrobromide
    		Inhibitor
    Conessine dihydrobromide is an orally active and BBB-penetrable selective histamine H3 receptor antagonist. The pKi values of Conessine dihydrobromide for rat and human H3 receptors are 7.61 and 8.27, respectively. Conessine dihydrobromide is an inhibitor of the multidrug efflux pump system in Pseudomonas aeruginosa and can enhance the activity of antibiotics. Conessine dihydrobromide has antimalarial activity. Conessine dihydrobromide can also be used in the research of muscle atrophy.
    Conessine dihydrobromide
  • HY-106005R
    MMV390048 (Standard)
    		Inhibitor
    MMV390048 (Standard) is the analytical standard of MMV390048 (HY-106005). This product is intended for research and analytical applications. MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent.
    MMV390048 (Standard)
  • HY-13702R
    Nilutamide (Standard)
    		Inhibitor
    Nilutamide (Standard) is the analytical standard of Nilutamide. This product is intended for research and analytical applications. Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties.
    Nilutamide (Standard)
  • HY-W341759
    1,4-Dihydrazinylphthalazine
    		Inhibitor
    1,4-Dihydrazinylphthalazine (Compound 2) is an antiparasitic agent targeting Leishmania spp. 1,4-Dihydrazinylphthalazine is promising for research of tropical diseases, particularly cutaneous leishmaniasis.
    1,4-Dihydrazinylphthalazine
  • HY-19285AR
    Sulfaclozine sodium (Standard)
    		Inhibitor
    Sulfaclozine (sodium) (Standard) is the analytical standard of Sulfaclozine (sodium). This product is intended for research and analytical applications. Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine sodium (Standard)
  • HY-N15098
    Milbemycin α15
    		Inhibitor
    Milbemycin α15 possess a potent antiparasitic activity, including acaricidal, insecticidal and nematocidal activities.
    Milbemycin α15
  • HY-B0945R
    Nitromide (Standard)
    		Inhibitor
    Nitromide (Standard) is the analytical standard of Nitromide. This product is intended for research and analytical applications. 0
    Nitromide (Standard)
  • HY-122461
    Glycobiarsol
    		Inhibitor
    Glycobiarsol is an organic arsenical compound, which can be used as an amoebicidal agent. Glycobiarsol exhibits toxicity and side effects.
    Glycobiarsol
  • HY-N15094
    Milbemycin α13
    		Inhibitor
    Milbemycin α13 (Meilingmycin B) is an antibiotic and has the effect of killing nematodes and mites.
    Milbemycin α13
  • HY-113907
    SDZ-285604
    		Inhibitor
    SDZ-285604 (VNF) is a T. cruzi CYP51 inhibitor and can be used for study of Trypanosoma cruzi infection.
    SDZ-285604
Parasite Isoform Comparison

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